Genetic Coeliac Disease
A genetic test that looks for HLA-DQ2 and HLA-DQ8 markers associated with coeliac disease.
What does it check?
- HLA-DQ2.5 (DQA1*05:01 and DQB1*02:01)
- HLA-DQ2.2 (DQA1*02:01 and DQB1*02:02)
- HLA-DQ8 (DQA1*03:01 and DQB1*03:02)
Who may benefit?
People with gastrointestinal symptoms on a gluten-free diet where standard antibody tests are inconclusive, individuals with a family history of coeliac disease, or those with autoimmune disorders.
Genetic Coeliac Disease
What is it?
A genetic test that looks for HLA-DQ2 and HLA-DQ8 markers associated with coeliac disease.
Who may benefit?
People with gastrointestinal symptoms on a gluten-free diet where standard antibody tests are inconclusive, individuals with a family history of coeliac disease, or those with autoimmune disorders.
Important information
Almost all people with coeliac disease carry HLA-DQ2 or HLA-DQ8, so the absence of these markers virtually rules out coeliac disease. However, possessing these markers does NOT mean you have or will develop the condition, as they are present in roughly 30% of the general population.