Wegovy (Semaglutide)
Wegovy (semaglutide) is an FDA & MHRA-approved once-weekly weight loss injection. It mimics the natural body hormone GLP-1 to regulate appetite and food intake, helping you feel fuller for longer and lose up to 15% body weight when combined with lifestyle guidance.
Wegovy Titration Tiers
New to Wegovy? All new patients begin on 0.25mg for Weeks 1–4.
Recommended for all new Wegovy patients (Weeks 1-4)
Wegovy pens are purchased at cost price directly from the pharmacy, facilitated by Smiths Medical Group.
What is Wegovy?
Wegovy is a prescription medication formulated for weight loss and long-term weight management.
Active Ingredient
Wegovy contains semaglutide, which acts on body pathways regulating appetite and calorie intake.
How It Works
It increases feelings of fullness, reduces hunger cravings, and slows stomach emptying so you consume fewer calories effortlessly.
Administration
Wegovy is taken as a convenient once-weekly subcutaneous injection.
Suitability
Wegovy is suitable for adults with obesity (BMI over 30) or overweight adults (BMI over 27) with weight-related conditions.
Effectiveness
In clinical trials, adults taking Wegovy lost an average of 15% of their body weight over 68 weeks.
Side Effects & Safety
Common side effects include mild nausea, constipation, or indigestion. Gradual titration starting at 0.25mg minimises these effects.
Wegovy Dosing Schedule
Wegovy is taken once a week. We follow a clinically structured schedule to gradually increase the dosage every 4 weeks, helping your body adapt while maximising results.
Weeks 1–4
Start with a dose of 0.25mg once a week to let your body adjust smoothly to semaglutide.
Weeks 5–8
Increase the dose to 0.5mg weekly, building appetite control while monitoring tolerance.
Weeks 9–12
Increase to 1.0mg weekly to further reduce food noise and support weight loss.
Weeks 13–16
Escalate to 1.7mg weekly in preparation for the full maintenance dose level.
Weeks 17+
Reach the maximum licensed 2.4mg weekly maintenance dose for maximum long-term weight management.
Clinical Guidance on Titration:
This structured dosing schedule helps minimise side effects and allows your body to adapt to each new dose level gradually. Always follow your healthcare provider's instructions and discuss any concerns with Matthew Smith (ANP) during your monthly reviews. Do not escalate faster than the 4-week titration guidelines.
How to Use Your Wegovy Pen
Watch our step-by-step video to see how your Wegovy pen works, how to prepare the dose, and how to comfortably self-administer at home.
Check Your Pen
Confirm medicine is clear and attach a new needle
Select Dose
Turn dose counter until dose symbol is shown
Inject Once Weekly
Inject into abdomen, thigh, or upper arm and hold for 6 seconds
Dispose Safely
Safely discard needle in your sharps bin
Targeted Blood Panels for Optimised Weight Management
At Smiths Medical Group, we provide an enhanced level of clinical diligence. By incorporating comprehensive blood analysis before and during your weight loss journey, we ensure your treatment is precisely tailored, safe, and protective of your long-term metabolic health.
Weight Loss Commencement Profile
Conducted prior to starting weight management therapy to establish your baseline organ function, screen for underlying metabolic or hormonal factors, and ensure prescribing suitability.
What It Evaluates:
- Liver & Kidney Function: Confirms healthy organ clearance for weight loss medications.
- Full Glycaemic Assessment (HbA1c & Fasting Blood Sugar): Screens for undiagnosed insulin resistance or pre-diabetes.
- Comprehensive Lipid Profile: Evaluates cholesterol markers to track cardiovascular improvements over time.
- Thyroid Function (TSH & Free T4): Rules out underlying thyroid dysfunction that can suppress metabolic rate.
Weight Loss Monitoring Profile
Recommended periodically during active weight loss to track metabolic response, verify nutritional balance, and adjust your treatment parameters with objective clinical data.
Key Monitoring Clinical Benefits:
- Nutritional & Micronutrient Status: Checks key micronutrient and vitamin levels as dietary intake reduces.
- Metabolic Trend Tracking: Measures progress in blood glucose, triglycerides, and liver enzymes during weight reduction.
- Dose Optimisation: Informs decisions on dosage titration to ensure efficacy while minimising unwanted side effects.
- Physician & ANP Oversight: Provides clear objective markers for review by Matthew Smith (ANP) and Dr Iqbal (Medical Director).
Why Blood Monitoring Provides a Superior Standard of Care
Standard online weight loss services often issue prescriptions based solely on online questionnaires without objective health data. At Smiths Medical Group, offering dedicated Commencement and Monitoring Blood Profiles elevates your care to a premium clinical standard.
Identifies pre-existing organ or metabolic conditions before starting active medication.
Provides clear, objective biomarker metrics demonstrating internal health improvements alongside scale weight.
Conducted with expert review from Advanced Nurse Practitioner Matthew Smith and Medical Director Dr Iqbal.
Wegovy (Semaglutide) FAQs
Answered by Matthew Smith, Advanced Nurse Practitioner.
Start Your Wegovy Treatment Plan
Book your initial £50 consultation with Matthew Smith, Advanced Nurse Practitioner, to establish eligibility and baseline health markers.
Smiths Medical Group Ltd